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Lifestyle

Good news for sweet tooths: Going sugar-free can mess with your gut and metabolism: study

News RoomBy News RoomJune 13, 2026No Comments4 Mins Read
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Good news for sweet tooths: Going sugar-free can mess with your gut and metabolism: study
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Here’s some surprisingly sweet science.

Americans consume far more sugar than experts recommend — a habit linked to obesity, diabetes, heart disease and a host of other health problems.

But while many people could benefit from scaling back their intake, a new study found that cutting sugar out entirely may backfire in unexpected ways.

“Completely removing sucrose from a low-fat diet may unexpectedly disrupt gut health and promote inflammation and metabolic dysfunction,” Dr. Rasheed Ahmad, principal scientist and head of the Immunology & Microbiology Department at the Dasman Diabetes Institute in Kuwait, said in a press release.

The findings, presented Saturday at the Endocrine Society’s annual meeting in Chicago, suggest that “balanced nutrition is more important than simply eliminating sugar,” he said.

To investigate the effects of a sugar-free diet, Ahmad and his colleagues compared two groups of mice over a 16-week period.

One group was fed a low-fat diet that contained sucrose, a type of table sugar, while the other received a low-fat diet with no sucrose at all.

Throughout the study, researchers tracked a range of health markers, including glucose tolerance — or how well the body processed sugar — how sensitive it was to insulin, levels of metabolic hormones, gut bacteria, and signs of inflammation in the colon and liver.

By the end of the 16-week study, both groups of mice weighed about the same.

Notably, however, the mice on the sucrose-free, low-fat diet developed a range of health issues, including impaired glucose control, insulin resistance, imbalances in gut bacteria, intestinal inflammation, and changes associated with fatty liver disease.

“The findings suggest that complete removal of sucrose from a low-fat diet may negatively affect gut microbiota and metabolic health,” Ahmad said.

“The study highlights the importance of maintaining balanced dietary carbohydrates to support gut and immune homeostasis.”

Before the study, the researchers noted that the effects of eliminating sugar from a low-fat diet hadn’t been understood.

Now, Ahmad believes the findings could help reshape how experts think about nutrition.

“This research may influence future dietary recommendations by emphasizing the importance of maintaining a healthy gut microbiome rather than focusing only on sugar restriction,” Ahmad said.

“In the long term, these findings could help improve strategies for preventing and managing metabolic disorders, fatty liver disease and chronic inflammatory conditions.”

But that doesn’t mean you should give in to your sweet tooth entirely.

Sugar naturally exists in everyday whole foods like fruits, vegetables, grains and dairy, which also come packed with fiber, vitamins, antioxidants, protein and calcium.

These nutrients help support overall health and slow digestion, allowing the body to absorb natural sugars more gradually and deliver a steadier stream of energy instead of a quick spike.

The real problems come in when sugar is added during processing, like sweeteners that are poured into foods and drinks to boost flavor or extend shelf life.

Consuming too many added sugars can drive up blood pressure, fuel chronic inflammation, contribute to tooth decay and lead to weight gain. Over time, it can increase the risk of serious conditions like type 2 diabetes and heart disease.

It can also set off a rollercoaster inside the body, causing blood sugar spikes followed by sharp crashes that leave you feeling tired, sluggish and irritable.

In the US, research shows that the biggest sources of added sugar are sugary drinks and baked goods.

On average, Americans consume about 17 teaspoons of added sugar per day — more than two to three times the recommended limit for men and women, respectively.

That adds up fast, amounting to a whopping 60 pounds of added sugar a year.

For optimal health, the American Heart Association recommends that men consume no more than 9 teaspoons of added sugar per day. Women, on the other hand, should limit their intake to 6 teaspoons daily.

Read the full article here

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