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Rosie O’Donnell Shows Off Weight Loss: ‘I Can’t Believe This is Me’

News RoomBy News RoomMay 25, 2025No Comments5 Mins Read
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Rosie O’Donnell Shows Off Weight Loss: ‘I Can’t Believe This is Me’
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Rosie O’Donnell showed off her weight loss following her recent move to Ireland.

The former Rosie O’Donnell Show host, 63, shared a new photo via Instagram on Saturday, May 24, in which she credited the weight loss medication Mounjaro for her new look.

“I cant believe this is me now,” O’Donnell wrote, along with hashtagging the photo with “mounjaro,” “weightloss” and “bodydismorphia.”

Mounjaro is an injectable medication that is used to treat type 2 diabetes and has shown effectiveness in weight loss.

O’Donnell first shared with her social media followers in March that she was taking Mounjaro as part of her diabetes treatment.

 

“I’ve lost more weight. I am on Mounjaro for my diabetes and one of the side effects is you lose weight,” she said. “But it’s also because I had a chef for over two years in Los Angeles and I don’t have a chef now. It’s me cooking for Clay and me.”

She continued, “I’m one of those people who always had a weight issue and now that I’m a size large — instead of an XL or a XXL — I find it shocking. I really do. I find it completely shocking.”

Mob Wives star Renee Graziano recently revealed a 52-pound weight loss that she credited, in part, to using Mounjaro. She added that “right supplements” and “doing all the work behind [her] insecurity” were also responsible for her fitness journey.

“I’ve battled self-criticism in the past! Ripped myself down to the ground!!” Graziano, 57, wrote via Instagram. “I truly was so sick and tired of my life and my inability to lose weight so I thought I’d eat until I felt better THAT NEVER HAPPENED, I felt like I was constantly falling short—of how I ‘should’ look, feel, and keep up with what society tells us is acceptable.”

Graziano went on, “That’s why, when I see photos that show the real, visible change, my clear eyes and genuine smile, I have to share. I want everyone to know if I can do it, you can do it! It’s all possible!!”

Amy Schumer has praised Mounjaro as well, revealing she adjusted more easily to the injectable medication than its competitor medication Wegovy. (According to WebMD, Mounjaro is classified similarly to other drugs such as Wegovy or Ozempic because they all contain GLP-1, which assists in weight loss. Mounjaro is designed to help diabetes patients with weight management, with common side effects including nausea and diarrhea.)

“Three years ago, I tried Wegovy,” Schumer, 43, said in an Instagram video in March. “I was puking, I couldn’t handle it. I don’t know if they’ve changed the formula, whatever. But anyway, I went on this Telehealth meeting with [virtual care clinic] Midi Health, and it was cheap. I wanted to try it myself ‘cause I wanted to recommend it to my friends who are nurses and teachers.”

She added, “They put me on estrogen and progesterone because I realized I was in perimenopause and my symptoms from being perimenopause have disappeared. My hair is fuller, my skin is better, I have more energy, I want to get down more, if you know what I mean. I’m talking about sex. So that’s been great and Mounjaro’s been great.”

Meanwhile, O’Donnell moved from the U.S. to Ireland with her 12-year-old child, Clay, in January. The actress exclusively told Us Weekly in April that the pair were now settled in Dublin.

“There’s a great, great school there. And Clay has done very well. And they were really welcoming,” O’Donnell told Us. “And I love the little town, the little village. It’s in the heart of Dublin, but it’s still a village where you know the name of the grocer and you know the name of the cashiers. People are unbearably kind in a way that shocks me every single day.”

O’Donnell admitted to Us that she was surprised to see Ellen DeGeneres and her wife Portia de Rossi leave the U.S. as well, to resettle in the English countryside.

“I’ve never really known Ellen to say anything political in her life, so I was surprised to read that she left because of President Trump. Like, that shocked me, actually,” O’Donnell told Us. “I’ve been a political person my whole life, not better or worse, it’s just a different way to be in the world. I was very clear about the reason why I was leaving, and I don’t think it came as a surprise to anyone. We’re not really in each other’s worlds, and it’s been kind of awkward but you know what? I wish her the best. I wish that she has peace and love in her life and that she is OK.”

O’Donnell’s fans will next see her in season three of Sex and the City sequel show And Just Like That…, which premieres on Max Thursday, May 29, and new episodes drop weekly.



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