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The Indiana State Sycamores visit the Purdue Boilermakers on Friday, September 4, 2026 at 7:00 p.m. ET from Ross-Ade Stadium, West Lafayette, IN.
Purdue opens its season at home against Indiana State, an FCS opponent already 0-1 after a 21-23 loss to Southeast Missouri State in Week 0. The Boilermakers have won their last two meetings with the Sycamores by a combined 105-0, including a 49-0 result in 2024. Purdue is a 36.5-point favorite at DraftKings, with the total set at 56.5.
Below, we’ll give you all the details you need to know about how to watch this game.
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