The Los Angeles Chargers visit the Buffalo Bills on Sunday, September 27, 2026 at 1:00 p.m. ET from Highmark Stadium, Orchard Park, NY.
The Bills enter at 2-0 on the season, while the Chargers are 0-2.
Buffalo has scored 77 points without a giveaway and has converted 57.1 percent of third downs. Los Angeles has allowed 393 yards and 26 points per game with 3 sacks through two weeks.
Buffalo has 7 sacks but has allowed 31 points per game. Los Angeles carries a minus-4 turnover margin and has allowed 273 passing yards per game while Buffalo has allowed 95 rushing yards per game at 3.7 yards per carry.
The Bills are 7-point favorites over the…
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